Naslov
Neisser's influence on serodiagnosis of syphilis in Croatia

Autori
Lipozenčić, Jasna ; Marinović, Branka

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
13th Alpe-Danube-Adria STD Congress and infections of the Skin. Abstract Volume. / - Trst, 2007

Skup
13th Alpe-Danube-Adria STD Congress and infections of the Skin

Mjesto i datum
Trst, Italija, 09.11.2007. - 10.11.2007

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Neisser's influence; serodiagnosis syphilis; Croatia

Sažetak
There are world wide well known Albert Neisser's scientific experimental works in syphilis research. In Laboratory for serodiagnosis of syphilis at the Department of Dermatology and Venerology University Hospital Center Zagreb and School of Medicine in Zagreb, Croatia we are very familiar with Neisser and Wassermann importance in diagnosis of syphilis. Amazing is experimental Neisser’ s work of antibodies against antigens of Treponema pallidum. Albert Ludwig Siegmund Neiser was well known German physician, bacteriologist and dermatovenerologist, founder of gonococcus important for his work on lepra and the contagion of syphilis in man and animals. He was born in 1855 in (Swidnica, Poland), and died in 1916 in Breslau (Wroclaw). The most significant advances in the diagnosis and treatment of venereal diseases were made in the late nineteenth and early twentieth century, and Albert Neisser was one of the greatest names in this field. The time after 1906 when syphilis dominated the field of dermatovenerology in Croatia were introduced many Laboratories to which Wassermann-Neisser reaction was used as a serologic test for identification of syphilis. Janko Thierry (1874-1938) introduced in Laboratory for blood testing Wassermann-Neisser reaction 1906 in Zagreb. In 1910, when the first “ magic bullet” Salvarsan was still tested by Pavel Ehrich (1854-1915), Thierry (Zagreb) inaugurated it in 11 patients, and after that 50 patients more. The Wassermann’ s – Neisser reaction was introduced in Croatia (Osijek) by Aleksandar Blašković (1911-1914). Pavel Šavnik (Zagreb), 1919 published paper on Wassermann reaction and Spirochaeta pallida (1921), in our journal Liječnički vjesnik. It is also known that Šavnik and Kogoj cooperated and published a paper together in the Archiv für Dermatologie and Syphilis in 1922. Academician Franjo Kogoj in Croatia founded in Zagreb Serodiagnostic laboratory for syphilis in 1928. Important serologic test was Wassermann-Neisser method of complement reaction in syphilis diagnosis in Department of Dermatology and Venerology University Hospital Center Zagreb until 2000. Nowadays, serodiagnosis of syphilis is based on VDRL test, rapid test (RPR) and specific antitreponomal tests: TPHA, IgG, and IgM-FTA ABS test. Many scientific works according diagnosis syphilis were made during 80 years.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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