Pregled bibliografske jedinice broj: 318425
Distribution of the relative total amount of constitutive heterochromatin in somatic cells and potential zygotes of individuals with different reproductive disorders
Distribution of the relative total amount of constitutive heterochromatin in somatic cells and potential zygotes of individuals with different reproductive disorders // Final Programme and Abstract Book
Zagreb, 1994. str. 56-56 (poster, domaća recenzija, sažetak, znanstveni)
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Naslov
Distribution of the relative total amount of constitutive heterochromatin in somatic cells and potential zygotes of individuals with different reproductive disorders
Autori
Buretić-Tomljanović, Alena ; Radojčić, Anđelka
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Final Programme and Abstract Book
/ - Zagreb, 1994, 56-56
Skup
1. HRVATSKI KONGRES HUMANE GENETIKE s međunarodnim sudjelovanjem
Mjesto i datum
Zagreb, Hrvatska, 22.09.1994. - 25.09.1994
Vrsta sudjelovanja
Poster
Vrsta recenzije
Domaća recenzija
Ključne riječi
constitutive heterochromatin; reproductive disorders
Sažetak
The quantitative amalysis of constitutive heterochromatin has been performed in order to investigate its possible role in human reproduction and development. For this purpose, 30 couples with different fertility disorders and 30 infertile men were evaluated. The clinical diagnoses of couples were: the history of repeatedspontaneous abortions, stillborn child, birth of a malformed child or sterility. For infertile men diagnoses were: hypogonadism, confirmed azoospermia or oligozoospermia. the control group is represented by 7 couples with one or more healthy children, and without the history of spontaneous abortions or abnormal children. All individuals included in the investigation have normal karyotype. M ; easuring of constitutive heterochromatinwas performed on GTG-banded metaphase chromosomes. The relative amount of constitutive heterochromatin was determined by q/(p+q) transformation. Its relative total amount in somatic cells and minimal and maximal relative total amount in potential zygotes of the couples were determined by measuring chromosome's pair 1, 9 and 16 in five mitosis of visaully the same degree of chromosomal condensation. The distribution of the investigated parameters is normal in both test groups and a control group. The difference between their mean values failed to show statistically significant difference (p>0, 05).
Izvorni jezik
Engleski
Znanstvena područja
Biologija, Temeljne medicinske znanosti
