Naslov
Malignant transformation of oral lichen planus

Autori
Manojlović, Spomenka ; Mravak Stipetić, Marinka ; Lukšić, Ivica ; Macan, Darko ; Manojlović, Zoran

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts of the 21st European Congress of Pathology ; PP4 Gynecopathology ; PP4-164 ; u: Virchows Archiv 451 (2007) (2) / - : Springer, 2007, 544-545

Skup
European Congress of Pathology (21 ; 2007)

Mjesto i datum
Istanbul, Turska, 08.09.2007. - 13.09.2007

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
oral lichen planus; malignant transformation; oral cancer

Sažetak
We present fivepatients with squamous cell carcinoma of the buccal mucosa arised on the pre-existing oral lichen planus. Immunohistochemical analysis of the precursor lesions was performed by using p53 and Ki-67 antigens, and compared with the unaffected mucosa of the same patient, as well as with the matched control patient's mucosa. Clinical diagnosis of OLP has to be confirmed by histopathological analysis. As a premalignant lesion, OLP need to be assessed by use of immunohistochemical and genetic markers as well. Further research is essential for better understanding of the mechanisms and propensity of some OLP lesions to undergo malignant transformation.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti, Dentalna medicina

POVEZANOST RADA