Naslov
Modelling of Epitope-Paratope Interaction Using Molecular Recognition theory

Autori
Štambuk, Nikola ; Konjevoda, Paško ; Vikić-Topić, Dražen ; Pokrić, Biserka

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Book of Abstracts, MATH/CHEM/COMP 2007, Dubrovnik, Croatia, June 11-16, 2007 / Graovac, Ante ; Pokrić, Viserka ; Smrečki, Vilko - Zagreb : Hum naklada, 2007

ISBN
978-953-6954-26-1

Skup
MATH/CHEM/COMP 2007, The 22nd International Course & Conference on the Interfaces among Mathematics, Chemistry & Computer Sciences, Dubrovnik, Croatia, June 11-16, 2007

Mjesto i datum
Dubrovnik, Hrvatska, 11.06.2007. - 16.06.2007

Vrsta sudjelovanja
Pozvano predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
modelling; epitope; paratope; interactions; molecular; recognition

Sažetak
We investigated the modelling of epitope-paratope interactions using Molecular Recognition Theory. It is shown that the standard algorithm according to Kyte and Doolittle may be combined with complex methods of the secondary structure prediction to extract the information relevant for the epitope location and modelling. Described concept represents useful and simple set of procedures for deriving new biologically active peptides and antibodies and also performing modulation of peptide-receptor interaction.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

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