Pregled bibliografske jedinice broj: 316901
Azathioprine in Dermatology
Azathioprine in Dermatology // Acta Dermatovenerologica Croatica, 15 (2007), 4; 264-268 (recenziran, pregledni rad, stručni)
CROSBI ID: 316901 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Azathioprine in Dermatology
Autori
Bardek, Ivana ; Milavec Puretić, Višnja ; Lipozenčić, Jasna
Izvornik
Acta Dermatovenerologica Croatica (1330-027X) 15
(2007), 4;
264-268
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, stručni
Ključne riječi
azathioprine; azathioprine use in dermatology; adverse effects of azathioprine
Sažetak
Azathioprine is a synthetic purine analog derived from 6-mercaptopurine. It is a purine antagonist and its active metabolites act by disrupting the function of endogenous purines. It has a cytotoxic and immunosuppressive mechanism of action. It and Venereology is used in dermatology for treatment of immunobullous diseases, generalized eczematous disorders and photodermatoses. There is an enzyme in the metabolism of azathioprine called thiopurine s-methyltransferase (TPMT). It is very important to measure the TPMT activity before initiating therapy so that proper dosing of azathioprine can be achieved.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Projekti:
0108166
Ustanove:
Medicinski fakultet, Zagreb,
Klinički bolnički centar Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
Uključenost u ostale bibliografske baze podataka::
- MEDLINE
- Chemical Abstracts
- Excerpta Medica
- Index Medicus
- SCIE
