Pregled bibliografske jedinice broj: 31382
Cultivated rat embryo as a model for investigation of the role of DNA methylation in development
Cultivated rat embryo as a model for investigation of the role of DNA methylation in development // Knjiga sažetaka / Radačić, M. i Stojković, R. (ur.).
Zagreb: IRB, Zagreb, 1996. str. 36-36 (poster, domaća recenzija, sažetak, znanstveni)
CROSBI ID: 31382 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Cultivated rat embryo as a model for investigation of the role of DNA methylation in development
Autori
Vlahović, Maja ; Bulić-Jakuš, Floriana ; Crnek, Vesna ; Šerman, Draško
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Knjiga sažetaka
/ Radačić, M. i Stojković, R. - Zagreb : IRB, Zagreb, 1996, 36-36
Skup
Pokusne životinje u znanstvenim istraživanjima, Prvi hrvatski simpozij s međunarodnim sudjelovanjem
Mjesto i datum
Zagreb, Hrvatska, 28.10.1996. - 29.10.1996
Vrsta sudjelovanja
Poster
Vrsta recenzije
Domaća recenzija
Ključne riječi
DNA methylation; rat embryo culture; development
Sažetak
DNA methylation in vertebrate cells provides an important mechanism for distinguishing genes that are active from those that are not. Its importance in early development is clearly demonstrated by the finding that even a modest reduction in DNA methylation causes severe developmental abnormalities and even death of embryos during organogenesis. 9 day old rat egg cylinders cultivated with the demethylating agent 5-azacytidine showed significantly improved differentiation of myotubes, cartilage and neuroblasts.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
