Naslov
Immunological reactivity in elderly patients with chronic lymphocytic leukemia (CLL)

Autori
Handl, Sonja ; Sabioncello, Ante ; Mažuran, Renata ; Rabatić, Sabina ; Svoboda-Beusan, Ivna ; Milić, Nedjeljko ; Silobrčić, Vlatko ; Dekaris, Dragan

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
1. kongres imunologa Jugoslavije : knjiga sažetaka ; u: Periodicum biologorum 88 (1986) (Suppl. 1/A) / - , 1986, 477-479

Skup
Kongres imunologa Jugoslavije (1 ; 1985)

Mjesto i datum
Opatija, Jugoslavija, 21.10.1985. - 25.10.1985

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Domaća recenzija

Ključne riječi
lymphocyte subpopulations ; rosette teshniques ; NK activity ; phagocytosis ; ADCC ; digestion ; random mobility

Sažetak
Chronic lymphocytic leukemia (CLL) is a disease of elderly people. As elderly people in general have impaired humoral and cellular immunity, we compared cellular markers and immune functions of CLL patients (60-87 years of age) with age matched controls as well as with younger controls (20-60 years). T lymphocytes and NK activity were decreased while digestion function of phagocytes was increased in patients as compared to the age matched controls. If compared to younger controls, both T and B lymphocytes, NK activity and phagocytic functions (ingestion and ADCC) were impaired. Because this discrepances, due to age, it is necessary to deal with age-matched controls.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

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