Naslov
Biphenotype acute leukaemia with translocation t(3 ; 7)(q21 ; q34-35)

Autori
Mrsić, Sanja ; Batinić, Drago ; Boban, Dubravka ; Marković-Glamočak, Mirjana ; Sučić, Mirna ; Stavljenić-Rukavina, Ana ; Labar, Boris

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Fourth seminar New Trends in the Treatment of Acute Leukaemia / Mrsić, Mirando ; Labar, Boris - Zagreb : University Hospital Rebro Zagreb and European School of Oncology, 1996, 78-78

Skup
Fourth seminar New Trends in the Treatment of Acute Leukaemia

Mjesto i datum
Brijuni, Hrvatska, 14.09.1996. - 17.09.1996

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
Biphenotypic leukemia ; cytogenetics

Sažetak
Biphenotype acute leukaemia is a very rare type of leukaemia characterized by the oresence of myeloid and lymphoid markers. In this paper we describe a patient with acute leukaemia (AL) consisting of two cell-populations, one expressing CD34, HLA-DR and cytoplasmic CD3, and the other expressing myeloid marker CD13 and cytoplasmic CD3. Cytochemical analysis revealed 10% MPO+ cells and 70% PAS+ cells. Cytogenetic showed 46xx, T(3 ; 7)(q21 ; q34-35). This unique finding is of special interest since 3q21 has been seen in AML patients with abnormal platelets while 7q34-35 has been associated with TCR locus and associated with ALL.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Farmacija

POVEZANOST RADA