Pregled bibliografske jedinice broj: 311015
Influence of iron on proliferation and cell cycle kinetics on cultured malignant and nonmalignant cells
Influence of iron on proliferation and cell cycle kinetics on cultured malignant and nonmalignant cells // Oncology, 47 (1990), 5; 443-446 doi:10.1159/000226866 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 311015 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Influence of iron on proliferation and cell cycle kinetics on cultured malignant and nonmalignant cells
(Influence of iron on proliferation and cell cycle kinetics on cultured malignant and nonmalignant cell)
Autori
Flajsig, Igor ; Poljak-Blaži, Marija
Izvornik
Oncology (0030-2414) 47
(1990), 5;
443-446
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
iron ; cell cycle ; malignant cell
Sažetak
The presence of an iron-containing complex (FSC, ferric sorbitol citrate) in medium inhibited proliferation of malignant(KB, GHC) cells ; but did not appreciably alter the proliferation of normal (HBS, Varo) cells. Flow cytometric analysis showed considerable differences of malignant and normal cell growth kinetics. Addition of 200 microM Fe in medium suppressed malignant cell proliferation. An increased number of cell in G1 and early S phase suggested that iron excess blocked the cell cycle before beginning of DNA synthesis.
Izvorni jezik
Engleski
Znanstvena područja
Biologija
POVEZANOST RADA
Ustanove:
Institut "Ruđer Bošković", Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
