Naslov
Comparison of FPIA and GC/MS techniques for the analysis of drugs in post-mortem urine samples

Autori
Definis-Gojanović, Marija ; Sutlović, Davorka ; Suton, Jasmina ; Knezović, Zlatka, Kovačić, Zdravko

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Toxicology letters -Abstracts of EUROTOX 2001 / - , 2001

Skup
EUROTOX 2001

Mjesto i datum
Istanbul, Turska, 13.09.2007. - 16.09.2007

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
toxicological techniques; drugs; post-mortem

Sažetak
Post-mortem urine samples were collected from 25 persons who died in Split-Dalmatia County during 1999-2000 under suspicion of drug intoxication. Samples were analyzed by fluorescence polarization immunoassay (FPIA) and gas chromatography/mass spectrometry (GC/MS) in the aim of examination the possibility of FPIA usage as screening test method in determination of drug abuse in urine. The presence of the following drugs/metabolites was detected: opiates, methadone, amphetamines, tetrahydrocanabinol and cocain. The results have shown that FPIA is sufficiently reliable method for determination of addictive drugs (for each group the results match in 80% of analyses and more). Reliatively small number of samples comparised by this paper leaves this question open for further investigation.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Javno zdravstvo i zdravstvena zaštita

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