Naslov
Asociation between infection and appearance of myocardial infarction and stroce during the same hospitalisation

Autori
Cavrić, Gordana ; Bartolek, Dubravka ; Cmrečnjak, Jasna ; Jurić, Klara ; Filičić, Sanja ; Katalinić, Renata ; Kirin, Marijan ; Pehar, Mario

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstract of 20th ESICM Annual Congress, Germany, Berlin, 7-10 October, 2007 ; u Intensive Care Medicine Vol. 33 Supplement 2 / - , 2007, 0514-0514

Skup
20th Annual Congress of European Society of Intensive Care Medicine

Mjesto i datum
Berlin, Njemačka, 07.10.2007. - 10.10.2007

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
respiratory infection; myocardial infarction; stroke

Sažetak
INTRODUCTION. Appearance of myocardial infarction and stroke during the same hospitalization is rare and has great mortality ratio. It was expected these events to take place more often during winter and in connection with infection. METHODES. We have retrospectively analyzed data of 21 patients with diagnose of acute myocardial infarction and stroce during the same hospitalization, treated in our internal Intensive Care Unit from January 1995 to December 2006. None of thease patients were subjuated to thrombolytic therapy, percuataneus coronary intervention or coronary artery bypass graft. RESULTS. All included were Caucasian (who were maked 0.22% of total number of hospitalised patients during that period), 8 (38%) males and 13 (62%) females. Age of patients was between 49 and 85 years, mean 71+/-6.6 (CI 67-76). Six patients have survived (29%), and 15 died (71%)(5 males and 10 females). The average age of decreasedd males was 66+/-10.1 years (CI 54-79), and females was 76+/-10.1 (CI 69-83). Mean APACHE II score was 23+/-12 (CI 18-29), and mean GCS as 7+/-4 (CI 5-8). Most of the patients (9 patients or 43%) were dmitted during the winter, six in autum (29%), five in spring (24%) and in summer only one patient (4%). In 11 patients (52%) 6 males and 5 females) we found connection between current state with recent infection (within last month) or signs of infection on admission in ICU. Respiratory infection was found in 6 patients, urinary infection in 2, and in 2 cases we have found some other source of infection. Also we found significant connection between current state (myocardial infarction and stroce during sama hospitalisation) and infection during winter (p=0.0369) and positive correlation between infection and mortality of these patients (r=1.0000, p<0.0001). CONCLUSION. Acute infection like chronic inflammation can increase risk of vascular events although exact mechanisms are still unknown. We can expected these events more often during winter period when are respiratory infection more frequent. REFERENCE(S). Smeeth L, Thomas L, Hall J.A, Hubbard R, Farrington P, Vallance P. Risk of myocardial infarction and troce after acute infection and vaccination. N Engl J Med. 2004 ; 351:2611-2618.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA