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Pregled bibliografske jedinice broj: 306142

Inhibitory properties of nucleotides with difluoromethylenephosphonic acid as a phosphate mimic vs calf spleen purine nucleoside phosphorylase and effect of these analogues on the viability on human blood lymphocytes


Glavaš-Obrovac, Ljubica; Suver, Mirjana; Hikishima, Sadao; Yokomatsu, Tsutomu; Bzowska, Agnieszka
Inhibitory properties of nucleotides with difluoromethylenephosphonic acid as a phosphate mimic vs calf spleen purine nucleoside phosphorylase and effect of these analogues on the viability on human blood lymphocytes // Nucleosides, nucleotides & nucleic acids, 26 (2007), 8/9; 989-993 doi:10.1080/15257770701508513 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 306142 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Inhibitory properties of nucleotides with difluoromethylenephosphonic acid as a phosphate mimic vs calf spleen purine nucleoside phosphorylase and effect of these analogues on the viability on human blood lymphocytes

Autori
Glavaš-Obrovac, Ljubica ; Suver, Mirjana ; Hikishima, Sadao ; Yokomatsu, Tsutomu ; Bzowska, Agnieszka

Izvornik
Nucleosides, nucleotides & nucleic acids (1525-7770) 26 (2007), 8/9; 989-993

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
purine nucleosid phosphorylase; difluoromethylenephosphonic acid; Hashimoto's thyroiditis

Sažetak
Several cyclic and acyclic 6-keto purine nucleotides with difluoromethylenephosphonic acid as phosphate mimic are proved to be potent inhibitors of mammalian purine nucleoside phosphorylase (PNP). Antiproliferative activity of these analogues on the growth of human blood lymphocytes was tested by MTT assay. Compared to inhibitory effects on the growth of human blood T-lymphocytes isolated from healthy donors, all analogues significantly slow down proliferation of lymphocytes isolated from patients with autoimmune thyroid disease – Hashimoto’ s thyroiditis.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biologija, Temeljne medicinske znanosti



POVEZANOST RADA


Projekti:
0127111
219-0982914-2176 - Mehanizam bioloških učinaka novih malih molekula na stanice tumora čovjeka (Glavaš Obrovac, Ljubica, MZOS ) ( CroRIS)

Ustanove:
Klinički bolnički centar Osijek,
Medicinski fakultet, Osijek

Poveznice na cjeloviti tekst rada:

doi www.tandfonline.com

Citiraj ovu publikaciju:

Glavaš-Obrovac, Ljubica; Suver, Mirjana; Hikishima, Sadao; Yokomatsu, Tsutomu; Bzowska, Agnieszka
Inhibitory properties of nucleotides with difluoromethylenephosphonic acid as a phosphate mimic vs calf spleen purine nucleoside phosphorylase and effect of these analogues on the viability on human blood lymphocytes // Nucleosides, nucleotides & nucleic acids, 26 (2007), 8/9; 989-993 doi:10.1080/15257770701508513 (međunarodna recenzija, članak, znanstveni)
Glavaš-Obrovac, L., Suver, M., Hikishima, S., Yokomatsu, T. & Bzowska, A. (2007) Inhibitory properties of nucleotides with difluoromethylenephosphonic acid as a phosphate mimic vs calf spleen purine nucleoside phosphorylase and effect of these analogues on the viability on human blood lymphocytes. Nucleosides, nucleotides & nucleic acids, 26 (8/9), 989-993 doi:10.1080/15257770701508513.
@article{article, author = {Glava\v{s}-Obrovac, Ljubica and Suver, Mirjana and Hikishima, Sadao and Yokomatsu, Tsutomu and Bzowska, Agnieszka}, year = {2007}, pages = {989-993}, DOI = {10.1080/15257770701508513}, keywords = {purine nucleosid phosphorylase, difluoromethylenephosphonic acid, Hashimoto's thyroiditis}, journal = {Nucleosides, nucleotides and nucleic acids}, doi = {10.1080/15257770701508513}, volume = {26}, number = {8/9}, issn = {1525-7770}, title = {Inhibitory properties of nucleotides with difluoromethylenephosphonic acid as a phosphate mimic vs calf spleen purine nucleoside phosphorylase and effect of these analogues on the viability on human blood lymphocytes}, keyword = {purine nucleosid phosphorylase, difluoromethylenephosphonic acid, Hashimoto's thyroiditis} }
@article{article, author = {Glava\v{s}-Obrovac, Ljubica and Suver, Mirjana and Hikishima, Sadao and Yokomatsu, Tsutomu and Bzowska, Agnieszka}, year = {2007}, pages = {989-993}, DOI = {10.1080/15257770701508513}, keywords = {purine nucleosid phosphorylase, difluoromethylenephosphonic acid, Hashimoto's thyroiditis}, journal = {Nucleosides, nucleotides and nucleic acids}, doi = {10.1080/15257770701508513}, volume = {26}, number = {8/9}, issn = {1525-7770}, title = {Inhibitory properties of nucleotides with difluoromethylenephosphonic acid as a phosphate mimic vs calf spleen purine nucleoside phosphorylase and effect of these analogues on the viability on human blood lymphocytes}, keyword = {purine nucleosid phosphorylase, difluoromethylenephosphonic acid, Hashimoto's thyroiditis} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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  • BIOSIS Previews (Biological Abstracts)
  • CA Search (Chemical Abstracts)


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