Naslov
Synthesis and Structural Study of the Acyclic Purine Nucleoside Analoques as Potential Antiviral Agents

Autori
Raić, Silvana ; Pongračić, Mario ; Vorkačpić-Furač, Jasna ; Hergold-Brundić, Antonija ; Nagl, Ante ; Mintas, Mladen

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, neobjavljeni rad, znanstveni

Izvornik
XIV. skup hrvatskih kemičara i IV. hrvatski simpozij o kemiji i tehnologiji makromolekula : Sinopsisi = Abstracts / - Zagreb : Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI) ; Hrvatsko kemijsko drustvo, 1995

Skup
XIV. skup hrvatskih kemičara i IV. hrvatski simpozij o kemiji i tehnologiji makromolekula

Mjesto i datum
Zagreb, Hrvatska, 06.02.1995. - 08.02.1995

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
aciklički purinski nukleozidni analozi
(acyclic purine nucleoside analogues)

Sažetak
Among many viral diseases, the acquired immunodeficiency syndrom (AIDS) has evolved despite intensive research on prevention and tretment into major epidemic in the last decade. Due to intensive efforts by chemists and molecular pharmacologists a number of nucleoside analogues has been discovered to posses potent antiviral activities against HIV the causative agent for AIDS. This investigation is concerned with the synthesis of the novel nucleoside analogues containing exocyclic pyrrolo moiety and acyclic side chains attached to the purine ring. The purpose of this work is to evaluate the novel compounds on various viruses causing opportunistic diseases including HIV, herpes and human hepatitis B virus.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

POVEZANOST RADA