Pregled bibliografske jedinice broj: 296193
Sterically Hindered N-Aryl-Pyrroles: Chiral Recognition by 1H NMR Cromatographic Separation of Enantiomers and Barriers to Racemization
Sterically Hindered N-Aryl-Pyrroles: Chiral Recognition by 1H NMR Cromatographic Separation of Enantiomers and Barriers to Racemization // 9.th IUPAC Conference on Physical Organic Chemistry
Regensburg, Njemačka, 1988. (poster, nije recenziran, sažetak, znanstveni)
CROSBI ID: 296193 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Sterically Hindered N-Aryl-Pyrroles: Chiral Recognition by 1H NMR Cromatographic Separation of Enantiomers and Barriers to Racemization
Autori
Vorkapić-Furač, Jasna ; Mintas, Mladen ; Burgemeister, Thomas ; Mannschreck, Albrecht
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Skup
9.th IUPAC Conference on Physical Organic Chemistry
Mjesto i datum
Regensburg, Njemačka, 21.08.1988. - 26.08.1988
Vrsta sudjelovanja
Poster
Vrsta recenzije
Nije recenziran
Ključne riječi
sterički zasjenjeni N-aril-piroli; kromatografsko odjeljivanje enantiomera
(sterically hindered; N-aryl-pyrroles)
Sažetak
Novel N-arly-3-formyl-2, 5-dimethylpyrroles 1-7 were synthesized by the condensation of the 2, 5-hexanedione with the corresponding anilines and subsequent Vilsmeier-Haack formylation of the pyrrole ring. Diastereomeric association complexes of racemic pyrroles 1-7 were studied by 1H NMR chemical shifts and splittings induced by the optically active auxiliary compound (+)-Eu(hfbc)3. Separation of enentiomers of 6 was achieved by liquid chromatography on triacetylcellulose. The barriers to partial rotation about the C-N in 6 was determined and their lower limits in 2 and 4 were estimated by variable temperature 1H NMR.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Ustanove:
Fakultet kemijskog inženjerstva i tehnologije, Zagreb
