Naslov
Frequency of Anticardiolipin, Antinuclear and Anti-b2 Glycoprotein I Antibodies in Children with Epilepsy

Autori
Markić, Joško ; Meštrović, Marija ; Valić, Ivan ; Sapunar, Ada ; Bošnjak, Nada

Izvornik
Collegium Antropologicum (0350-6134) 31 (2007), 3; 739-742

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
epilepsy; antinuclear antibodies; anticardiolipin antibodies; anti-b2-glycoprotein I antibodies

Sažetak
A high prevalence of epilepsies in specific immunological diseases suggests that the immune system may play a role in the pathogenesis of epilepsy or might be associated with it. In this study the frequency of anticardiolipin antibodies (aCL), antinuclear antibodies (ANA) and anti-b2-glycoprotein I antibodies (anti-b2-GPI) in 40 children with epilepsy and in 38 healthy subjects has been determined. Positive aCL were found in 3 patients, and anti-b2-GPI in 1 patient. In control group they were negative. ANA antibodies were negative in both groups. Duration of epilepsy < 1 year has been observed in all three patients with positive aCL. No statistically significant difference was found concerning the presence of these antibodies between patients and controls. There was no statistically significant correlation of age, sex, age at onset of epilepsy, duration of epilepsy, type of epilepsy, seizure frequency or specific antiepileptic medications with the presence of any measured antibodies.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA