Naslov
Multiple sclerosis: immunological profiles in the blood and cerebrospinal fluid

Autori
Rukavina, Daniel ; Sepčić, Juraj ; Ledić, Petar

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts 4th International congress of immunology of the International Union of Immunological Societies (IUIS) / Preud'homme J.L., Hawken, V.A.L. - Pariz : Societe francaise d'immunologie, 1980

Skup
4th International congress of immunology of the International Union of Immunological Societies (IUIS)

Mjesto i datum
Pariz, Francuska, 21.07.1980. - 26.07.1980

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
multiple sclerosis; blood; cerebrospinal fluid; immunology

Sažetak
Immunological and immunogenetic aspects of the multiple sclerosis were analyzed in 66 patients, clinically definite cases of the disease. According to the stage of the disease patients where divided in two groups: active and stable disease. Blood and cerebrospinal fluid specimens were analysed for lymphocyte subpopulations (active-T, total-T and B), immunoglobulins, antiviral antibodies and autoantibodies. Active disease patients blood is deficient in active-T comparing with stable phase and control. The level of total-T is also lower, but not that remarkably. There is not difference between patients and neurologic controls for antiviral antibodies. Unexpectedly, cerebrospinal T-lymphocytes are lower comparing with their level in the blood. Furthermore, HLA typing of the patients does not show any difference in the frequency of A3 and B7 comparing with the controls.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA