Naslov
Pleural mesothelioma and membranous nephropathy

Autori
Galešić, Krešimir ; Božić, Borka ; Heinzl, Renata ; Šćukanec-Špoljar, Mira ; Božikov, V.

Izvornik
Nephron (0028-2766) 84 (2000), 1; 71-74

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni

Ključne riječi
mesothelioma; membranous nephropathy; nephrotic syndrome

Sažetak
Underlying malignancy has been thought to be responsible for 5-10% of the cases of membranous nephropathy in adults, with the risk being highest in patients over the age of 60 years.Solid tumors such as carcinomas of lung or colon, are most often involved.It is presumed that tumor antigens are deposited in glomeruli ; this is followed by antibody deposition and complement activation, leading to epithelial cell and basement membrane injury and proteinuria due to the associated increase in glomerular permeability.We describe a patient with a resistant nephrotic syndrome and massive proteinuria due to membranous nephropathy associated pleural mesothelioma.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA