Pregled bibliografske jedinice broj: 283270
DIFFERENT CENTRAL ACTION OF STREPTOZOTOCIN AND ALLOXAN ON COGNITION
DIFFERENT CENTRAL ACTION OF STREPTOZOTOCIN AND ALLOXAN ON COGNITION // Acta Pharmacologica Sinica, Abstract of the 15th World Congress of Pharmacology / Paul M Vanhoutte (ur.).
Peking: Chinese Pharmacological Socety, 2006. (poster, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 283270 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
DIFFERENT CENTRAL ACTION OF STREPTOZOTOCIN AND ALLOXAN ON COGNITION
Autori
Šalkovic-Petrišić, Melita ; Lacković, Zdravko ; Riederer, Peter
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Acta Pharmacologica Sinica, Abstract of the 15th World Congress of Pharmacology
/ Paul M Vanhoutte - Peking : Chinese Pharmacological Socety, 2006
Skup
15th World Congress of Pharmacology
Mjesto i datum
Peking, Kina, 02.07.2006. - 07.07.2006
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
streptozotocin; alloxan; intracerebroventriculat; cognition
Sažetak
Streptozotocin and alloxan are selectively toxic for insulin producing/secreting cells, producin diabetes diabetes after peripheral but not central administration. Recently cognitive deficits in streptozotocin - intracerebroventriculary treated rats, while cognition in alloxan - icv treated rats has not been investigated. By means of Morris Water Maze Swimming Test, we have compared memory and learning function in STZ - and alloxan- icv treated rats, 3 months after icv drug treatment.Contrary to statistically significan decreament of of these function in STZ -icv rats, and some similar central neurochemical effects, ATZ - and alloxan- icv treatment demonstrate different influence on cognition, the later being deprived of any effect.
Izvorni jezik
Engleski
