Naslov
Učestalost poremećaja metabolizma glukoze i lipida u pretilih
(The frequency of impaired glucose and lipid metabolism in obesity)

Autori
Car, Antuanet ; Car, Nikica ; Poljičanin- Filipović, Tamara ; Pavlić-Renar, Ivana ; Metelko, Željko

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Liječnički vjesnik 2001 ; 123(Suppl. 1): Drugi hrvatski dijabetološki kongres. Knjiga sažetaka. / - , 2001

Skup
2. dijabetološki kongres

Mjesto i datum
Dubrovnik, Hrvatska, 04.06.2001. - 07.06.2001

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
debljina; oštećena tolerancija glukoze; šećerna bolest; lipidi
(obesity; impaired glucose tolerance; diabetes mellitus; lipids)

Sažetak
The aim of this investigation was to establish the relationship between obesity and IGT, DM and lipid metabolism disorders. Methods: The study included 251 persons divided into 3 groups according to their body mass index (BMI): the control group 1 (G1) comprised subjects with BMI <25 (N=46), group 2 (G2) included subjects with BMI >25, <30 (N=105), and group 3 (G3) subjects with BMI >30 (N=100). All subjects underwent standard OGTT and fasting lipidogram (typization according to Fredrickson). Results: There was a statistically significant difference in the occurrence of IGT and DM in G2 and G3 as compared with G1 (p<0.01). A statistically significant difference in fasting and post-load glycemia values was found between G2 and 3 as compared to G1 (p<0.01). A statistically significant positive correlation was found between glycemia and BMI (p<0.01). There was no statistically significant difference in the occurrence of pathological lipidograms between G2 and G3 as compared to G1. A statistically significant difference in HDL cholesterol (p<0.02) and triglycerides (p<0.01) was found between G3 and G1. A statistically significant correlation with BMI was found for HDL cholesterol (negative) and for triglycerides (positive). Conclusion: Group 2 and Group 3 comprised statistically significantly more patients with IGT and NIDDM than the control group. Fasting and post-load glycemia were statistically significantly lower in G1 as compared to G2 and G3. There were no statistically significant differences between the examined groups in the representation of pathological lipidograms. A statistically significant difference in HDL cholesterol and triglycerides was established between Group 1 and Group 3.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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