Naslov
Trabeculectomy with Mitomycin C in Glaucoma Associated with Uveitis

Autori
Novak-Lauš, Katia ; Mandić, Zdravko ; Iveković, Renata ; Koršić, Jadranka ; Tedesci-Reiner, Eugenia ; Masnec-Paškvalin, Sanja ; Bojić, Lovro

Izvornik
Collegium Antropologicum (0350-6134) 29 (2005), Supp 1; 17-21

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
trabekulektomija ; mitomicin C ; uveitični glaukom
(trabeculectomy ; mitomicyn C ; uveitic glaucoma)

Sažetak
The patients with uveitic glaucoma are at high risk of failure following drainage surgery because of yang age of these patients, preopertive long-term control of inflammation and postoperative complications. Twnety-two trabeculectomies performed in 22 patients with uveitic glaucoma were retrospectively evaluated to analyze the effect of intraoperative application of mitomicy C (MMC). Success rates, postoperative levels of intraocular pressure (IOP) and postoperative complications were studied. After a mean follow-up of 10.6 months (range, 5-28 months), 15 (68.2%) achieved IOP of 21mmHg or less without antiglaucoma medications. There were statistically significant reduction in IOP postoperatively during the period studied (p< 0.001). Early postoperative omplications included chorioidal detachment (9.1%), shallow anterior chamber (9.1%) , hyphema (13.6%) , macular edema (4.5%) and raised IOP (27.3%). Late postoperative complications included exacerbation of uveitis (4.5%), macular edema (4.5%), cataract (22.7%) and raised IOP (31.8 %). The eyes with raised IOP needed additional antiglaucoma medication. The results of this retrospective and uncontrolled study suggest that intraoperative application of MMC may be a good option for enhancement of short-term trabeculectomy success rates in patients with uveitic glaucoma

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA