Naslov
Complications and therapy due to transfusion of incompatible blood

Autori
Degoricija, Vesna ; Vučičević, Željko ; Mose, Jakov ; Šušković, Tomislav

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Slovenian Society of Intensive Care Medicine Second International Symposium on Intensive Care Medicine Book of Abstracts / Cerović, Ognjen - Bled : Slovenian Society of Intensive Care Medicine, 1993

Skup
Slovenian Society of Intensive Care Medicine Second International Symposium on Intensive Care Medicine

Mjesto i datum
Bled, Slovenija, 20.09.1993. - 22.09.1993

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
incompatible blood transfusion; complications; therapy

Sažetak
A 50-year old man with blood type 0, Rh +, experienced disseminated intravascular coagulation (DIC) with massive bleeding and post-transfusion hemolytic reaction (PTHR) following transfusion of incompatible blood type AB Rh + (7000 mL) during an operation of pharyngeal carcinoma with lymphoid metastases. DIC (PLT count 54, APTT 51 s, PT 27%, fibrinogen level 0.5 g/L, TT 21 s, fibrin monomers ethanol test ++) was treated with standard therapy, massive PTHR (RBC 1.57, Hb 55, htc 0, 16, RTC 0.107, bilirubine 345 micromol/L, LDH 1560 IU/L, haptoglobin very low, free hemoglobin high, hemoglobin and hemosiderin in urine positive) was treated with plasmapheresis. The patient developed acute renal failure (creatinine clearance 18 mL/min) and nosocomial sepsis (Acinetobacter sp.). This case report present clinical and laboratory features of complications due to incompatible blood transfusion and answer the following questions: 1. Why was the clinical feature of PTHR and DIC considered to be clinical feature of DIC and hemorrhagic shock? 2. Why were the cross-match reactions of patients serum and AB Rh + erythrocytes negative? 3. Why did massive intravascular hemolysis appear on the sixth day of the illness? 4. Is plasmapheresis the right choice for treatment of PTHR? The patient is alive and fully recovered. Laboratory studies are normal.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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