Naslov
Development of processes for biopharmaceutical production

Autori
Gaurina Srček, Višnja ; Slivac, Igor ; Radošević, Kristina ; Kmetič, Ivana ; Kniewald, Zlatko

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Marie Curie Workshop 2006 in Croatia and Serbia / - Beograd : Hrvatska akademija znanosti i umjetnosti (HAZU), 2006, 64-64

Skup
Marie Curie (MC) Workshop 2006 in Croatia and Serbia

Mjesto i datum
Beograd, Srbija; Zagreb, Hrvatska, 07.10.2006. - 11.10.2006

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Nije recenziran

Ključne riječi
animal cells; biopharmaceuticals; disposable bioreactor; IP; nanobiotechnology; viral vaccine

Sažetak
Industrial processes involving animal cells for the production of useful products like viral vaccines still seem to be uncommon. Although virus production in animal cells is an important part of industrial-scale production there are still demands for process development. Our goal was to apply new technologies for improvement of standard processes for biopharmaceutical production. We evaluated novel, disposable-bag bioreactor that uses wave action for mixing and transffering oxygen for BHK 21 C13 cell growth and Aujeszky’ s disease virus (ADV) production. Obtained results showed that this type of bioreactor showed higher AD virus titre and is suitable for production of other biopharmaceuticals. Using this novel technology, production time is significantly reduced lowering the costs of the whole process. Therefore, the advantages of this process could be objective of IP protection.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija

POVEZANOST RADA