Naslov
Tumour thickness in cutaneous melanoma in the Croatian region of Rijeka (1988-1997)
(Tumour thickness in cutaneous melanoma in the Croatian Region of Rijeka (1988-1997))

Autori
Gruber, Franjo ; Zamolo, Gordana ; Jonjić, Nives ; Pavlović, Lidia ; Brajac, Ines

Izvornik
3rd International Conference of Adjuvant Therapy of Malignant Melanoma

Vrsta, podvrsta
Ostale vrste radova, ostalo

Godina
1999

Ključne riječi
melanoma thickness; sites; smoking habit

Sažetak
Introduction: The incidence of melanoma is increasing faster than other malignant tumours world-wide. The tumour thickness (Breslow) is generally accepted as the most important prognostic factor. The aim of this retrospective study was to analyze the thickness of melanoma less or greater than 1.5mm by sex, age and site in patients with clinical stage I of melanoma. Methods: The date of 274 patients (145 females, 129 males) with clinical stage I melanoma seen at the Department of Dermatology between 1988-1997. were analyzed. Results: Female to male ratio showed a slight female predominance (1.1:1). Females present with significantly (p<0.05) thinner melanomas (43%) than males (27%). The proportion of patients with melanoma less than 1.5 mm thick decreased significantly with increasing age in both sexas, above 60 years (p<0.05). In both sexas the superficial spreading melanoma predominated over the nodular type and lentigo maligna melanoma. The incidence of nodular type was higher in males than in females. Site incidence showed a higher incidence of melanoma of the trunk in males and a significant higher incidence in females for lesions of lower limbs, especially of the superficial-spreading type. Regarding pigmented traits less thick melanomas occurred with more frequency among patients with fair skin and har. Conclusion: The obtained results indicate that in Rijeka region there is a difference between sexas at diagnosis, being earlier in females; this difference is not easy to explain, but emphasize the necessity for educational activities, early secondary prevention and the practising self-examination of the skin in males and older people.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita

POVEZANOST RADA