Naslov
"Epitope spreading" phenomenon in autoimmune bullous diseases

Autori
Lakoš Jukić, Ines ; Marinović, Branka

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Knjiga sažetaka 3.Kongresa hrvatskih dermatovenerologa s međunarodnim sudjelovanjem / - Split : Hrvatsko dermatovenerološko društvo Hrvatskog liječničkog zbora, 2006, 62-63

Skup
3.Kongres hrvatskih dermatovenerologa s međunarodnim sudjelovanjem

Mjesto i datum
Split, Hrvatska, 18.05.2006. - 21.05.2006

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Epitope spreading; autoimmune bullous diseases

Sažetak
"Epitope spreading" phenomenon can be defined as a development of immune, specific autoreactive lymphocyte T or B response to endogenous epitopes secondary to the release of self antigens during a chronic autoimmune or inflammatory disease. That means, in essence, that a primary autoimmune or inflammatory process may cause tissue damage in such a manner that certain protein components that are immunologically "hidden" from the immune system become "revealed" and evoke a secondary autoimmune response. It can occur within the same protein (intramolecular) and/or to other proteins within the same tissue or protein complex (intermolecular). We describe some interesting clinical cases of autoimmune bullous diseases in whome this interesting phenomenon might occured.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA