Pregled bibliografske jedinice broj: 266212
Streptozotocin-intracerebroventricularly treated rats: behavioral, neurochemical and structural resembling to the human sporadic type of Alzheimer's disease
Streptozotocin-intracerebroventricularly treated rats: behavioral, neurochemical and structural resembling to the human sporadic type of Alzheimer's disease // Alzheimer's & Dementia (supplement): Abstracts / Iqbal K, Winblad B (ur.).
New York (NY): Elsevier, 2006. (poster, međunarodna recenzija, sažetak, znanstveni)
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Naslov
Streptozotocin-intracerebroventricularly treated rats: behavioral, neurochemical and structural resembling to the human sporadic type of Alzheimer's disease
Autori
Salkovic-Petrisic, Melita ; Tribl, Florian ; Osmanovic, Jelena ; Schmidt, Manuela ; Hoyer, Siegfried ; Riederer, Peter
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Alzheimer's & Dementia (supplement): Abstracts
/ Iqbal K, Winblad B - New York (NY) : Elsevier, 2006
Skup
10th International Conference on Alzheimer's Disease and Related Disorders
Mjesto i datum
Madrid, Španjolska, 15.07.2006. - 20.07.2006
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
streptozotocin; Alzheimer's disease; brain; Akt/PKB; GSK-3
Sažetak
Streptozotocin-intracerebroventricularly treated rats (STZ-icv) have become an experimental model of sporadic Alzheimer's disease, and demonstrate resembling in cognitive deficits, alterations of Akt/PKB and GSK-3 enzymes of insulin receptor signaling cascade in the brain, as well as alterations of tau protein and accumulation of beta amyloid like aggregates in the brain.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
POVEZANOST RADA
