Pregled bibliografske jedinice broj: 265063
Topical photodynamic therapy in the treatment of malignant epidermal precancerous and cancerous lesions
Topical photodynamic therapy in the treatment of malignant epidermal precancerous and cancerous lesions // 6th International Symposium on Photodynamic Diagnosis and Therapy in Clinical Practice / H. Kostron, G. Jori (ur.).
Bressanone, Italija, 2006. (predavanje, međunarodna recenzija, sažetak, znanstveni)
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Naslov
Topical photodynamic therapy in the treatment of malignant epidermal precancerous and cancerous lesions
Autori
Kostović, Krešimir ; Lipozenčić, Jasna ; Pašić, Aida ; Zorc, Hrvoje ; Peršin, Antun ; Čeović, R ; Hrsan, Damir
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
6th International Symposium on Photodynamic Diagnosis and Therapy in Clinical Practice
/ H. Kostron, G. Jori - , 2006
Skup
6th International Symposium on Photodynamic Diagnosis and Therapy in Clinical Practice
Mjesto i datum
Bressanone, Italija, 10.10.2006. - 14.10.2006
Vrsta sudjelovanja
Predavanje
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
photodynamic therapy; photodynamic diagnosis
Sažetak
Photodynamic therapy (PDT) mediated by 5-aminolevulinic acid (ALA) has been introduced as a new anticancer therapeutic modalities. In January 2004, we have started topical PDT in the treatment selected group of patients with epidermal precancerous and cancerous lesions. Lesions were treated by topical application of 20% 5-ALA dissolved a proprietary oil-in- water emulsion. The ALA containing emulsion was applied under occlusive dressing 5-6 hours before illumination with non-coherent red light (630-700 nm, light dose 100-150 J/cm2). Prior to therapy diagnostics has been done using MEDILED-5 device. In our study 50 patients were included (twenty four men and twenty six women). Twenty patients had superficial basal cell carcinoma, eleven patients had other types of basal cell carcinoma, eleven had Bowen's disease and eight patients had other precancerous and cancerous lesions. Nine patients had recurrences after surgical excision and/or radiotherapy. In most patients complete or partial regression was achieved after one to three treatments. PDT is an alternative modality to surgical excision or superficial radiotherapy. This is also a good option for the treatment of recurrences after surgical treatment and superficial radiotherapy.
Izvorni jezik
Engleski
Znanstvena područja
Fizika, Kliničke medicinske znanosti
POVEZANOST RADA
Ustanove:
Institut "Ruđer Bošković", Zagreb,
Medicinski fakultet, Zagreb
