Pregled bibliografske jedinice broj: 264681
Macromolecular oxidation in the anisotonic suspensions of mouse spleen cells.
Macromolecular oxidation in the anisotonic suspensions of mouse spleen cells. // Cell biochemistry and function, 24 (2006), 3; 201-207 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 264681 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Macromolecular oxidation in the anisotonic suspensions of mouse spleen cells.
Autori
Bilić, Ivan ; Kovač, Zdenko
Izvornik
Cell biochemistry and function (0263-6484) 24
(2006), 3;
201-207
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Lipid and protein oxidatin; oxidative stress; osmotic stress; cell death
Sažetak
Macromolecular oxidative alterations have been analysed in vitro in anisotonic suspensions of mouse splenocytes. Both hypertonicity and hypotonicity induced the generation of thiobarbituric acid reactive species (TBARS) and carbonylation of the proteins, which took place along with cell death. Addition of antioxidants partially inhibited oxidative changes in isotonic and hypotonic suspensions. Anisotonic shock of mouse splenocytes proved to be an inducer of oxidative stress. The oxidative macromolecular alterations might contribute to pathogenesis of cell death caused by osmotic stress.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
Uključenost u ostale bibliografske baze podataka::
- Index Medicus
- Medline
