Naslov
Massive pulmonary embolism following heparin-induced thrombocytopenia

Autori
Vučičević, Željko ; Degoricija, Vesna ; Alfirević, Zrinka ; Sharma, Mirela

Izvornik
Acta Clinica Croatica (0353-9466) 44 (2005), 2; 109-113

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, prikaz, stručni

Ključne riječi
pulmonary embolism-chemically induced; thrombocytopenia-chemically induced; anticogulants-adverse effects; heparin-adverse effects

Sažetak
Immunomediated heparin-induced thrombocytopenia still presents a serious problem, especially when accompanied by thromboembolic complications. We report on a rare case of massive pulmonary embolism following perioperative prophylaxis with unfractionated and low-molecular-weight heparin. The lack of efficacious and safe heparin substitution only allowed for immediate heparin discontinuation and application of adjuvant therapy. A few days after heparin cessation the platelet count tended to return to normal, leading to the patient's full recovery and discharge from the hospital. Heparin therapy requires careful examination of previous history of heparin use as well as close platelet monitoring for up to three weeks of therapy cessation.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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