Pregled bibliografske jedinice broj: 261096
Gangliosides in brain ischemias
Gangliosides in brain ischemias // Neurologia Croatica, 43 (1994), 2; 75-85 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 261096 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Gangliosides in brain ischemias
Autori
Kalanj, Svjetlana
Izvornik
Neurologia Croatica (0353-8842) 43
(1994), 2;
75-85
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
brain ; gangliosides ; ischemia
Sažetak
The aim of this biochemical study was to explore the changes of gangliosides in brain tissue affected by ischemic damage. Samples of brain tissue with ischemic lesion (grey and white matter) (n=5), tissue adjacent to lesion (grey and white matter)(n=3) and contralateral control tissue (grey and white matter)(n=5) were analyzed. Results showed a significant decrease in the total amount of gangliosides in the samples with ischemic lesion as compared to control samples. Percentage distribution of individual gangliosides in lesion samples in comparison to control samples showed a decrease in gangliosides characteristic of neuronal cells (GD1a, GD1b, GT1b) due to ischemic destruction of neurons, and an increase in GM3 and GD3 gangliosides characteristic of glial cells but also of the lysosomal ganglioside catabolism.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
Uključenost u ostale bibliografske baze podataka::
- EMBASE (Excerpta Medica)
