Pregled bibliografske jedinice broj: 257302
Age-related changes in functions of peripheral blood phagocytes
Age-related changes in functions of peripheral blood phagocytes // Mechanisms of ageing and development, 45 (1988), 223-229 doi:10.1016/0047-6374(88)90004-8 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 257302 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Age-related changes in functions of peripheral blood
phagocytes
Autori
Rabatić, Sabina ; Sabioncello, Ante ; Dekaris, Dragan ; Kardum, Ika
Izvornik
Mechanisms of ageing and development (0047-6374) 45
(1988);
223-229
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
phagocytosis ; ingestion ; cell cytotoxicity ; antibody-dependent ; digestion age-related ; humans ; newborn ; child adult
Sažetak
Ingestion, digestion and antibody-dependent cell- mediated cytotoxicity (ADCC) of opsonized sheep red blood cells (SRBC), as effector functions of peripheral blood phagocytes, were studied in newborns, children, mature and aged adults. All tested functions changed non-synchronously during the lifetime. The ingestion was maximal in newborns, digestion in children and ADCC in mature adults. The ingestion was minimal in aged, but digestion was minimal both in newborns and aged. Such changes of phagocytes' functions could possibly contribute to differences in immune reactions of the age-groups studied. The study indicates the need for establishing age-adjusted normal values for major granulocyte and monocyte effector functions.
Izvorni jezik
Engleski
POVEZANOST RADA
Ustanove:
Imunološki zavod d.d.,
Klinička bolnica "Merkur"
Profili:
Ika Kardum-Skelin
(autor)
Ante Sabioncello
(autor)
Sabina Rabatić
(autor)
Dragan Dekaris
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
