Naslov
Dose-response relationship in the migration inhibition test using peritoneal cells and blood leucocytes of tuberculin sensitive guinea pigs

Autori
Sabioncello, Ante ; Dekaris, Dragan

Izvornik
Biomedicine (0300-0893) 26 (1977); 399-403

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
migration inhibition ; macrophage ; leucocyte ; dose-response ; in vitro ; skin test ; guinea pig

Sažetak
A comparison of the direct migration inhibition using peritoneal exudate cells and peripheral blood leucocytes from the same tuberculin sensitive guinea pigs was performed. Three antigen concentrations: 3, 15, and 75 microgram of PPD per ml were used. Both type of cells provided similar results except at early incubation intervals when leucocytes, in the presence of lower doses of the antigen, displayed stronger inhibition than peritoneal cells. Thus, in our study, peripheral blood leucocytes are at least equivalent to peritoneal exudate cells in the migration inhibition test.

Izvorni jezik
Engleski

POVEZANOST RADA