First report of CTX-M-extended-spectrum beta-lactamase- producing isolates from Croatia

Tonkić, Marija; Bedenić, Branka; Goić-Barišić, Ivana; Katić, Stjepan; Kalenić, Smilja; Kaufmann, Mary; Woodford, Neil; Punda-Polić, Volga

Pregled bibliografske jedinice broj: 256700

First report of CTX-M-extended-spectrum beta-lactamase- producing isolates from Croatia

Tonkić, Marija; Bedenić, Branka; Goić-Barišić, Ivana; Katić, Stjepan; Kalenić, Smilja; Kaufmann, Mary; Woodford, Neil; Punda-Polić, Volga

First report of CTX-M-extended-spectrum beta-lactamase- producing isolates from Croatia // Journal of Chemotherapy, 19 (2007), 1; 97-100 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 256700 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
First report of CTX-M-extended-spectrum beta-lactamase- producing isolates from Croatia

Autori
Tonkić, Marija ; Bedenić, Branka ; Goić-Barišić, Ivana ; Katić, Stjepan ; Kalenić, Smilja ; Kaufmann, Mary ; Woodford, Neil ; Punda-Polić, Volga

Izvornik
Journal of Chemotherapy (1120-009X) 19 (2007), 1; 97-100

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
extended-spectrum beta-lactamases; CTX-M beta-lactamases; Escherichia coli; cefotaxime
(extended-spectrum beta-lactamases; CTX-M-beta-lactamases; Escherichia coli; cefotaxime)

Sažetak
Five clinical Escherichia coli isolates from University Hospital Split, Croatia, with a CTX-M resistance phenotype (high level of resistance to cefotaxime and ceftriaxone) were screened for blaCTX-M alleles by PCR and confirmed to produce a group 1 CTX-M enzyme. ESBL phenotype was transferred by conjugation from 3 isolates to a rifampicin-resistant recipient strain. PFGE proved that two of these five strains were clonally related. This is the first report from Croatia of CTX-M type enzyme. Carbapenems could be recommended as antibiotics of choice for the treatment of infections caused by our CTX-M producing E. coli isolates.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA

Projekti:
108-1080114-0015 - Mehanizmi rezistencije na antibiotike u Gram-negativnih bakterija (Bedenić, Branka, MZOS ) ( CroRIS)
108-1080114-0017 - Genotipovi i činitelji virulencije uzročnika bolničkih infekcija (Budimir, Ana, MZOS ) ( CroRIS)
121-1080114-0306 - Djelovanje antibiotika na uzročnike biofilm infekcija (Vraneš, Jasmina, MZOS ) ( CroRIS)

Ustanove:
Medicinski fakultet, Zagreb,
Medicinski fakultet, Split

Profili:

Branka Bedenić (autor)