Pregled bibliografske jedinice broj: 25458
The Role of Corticosteroids and Cyclosporin A in Prevention of Corneal Graft Rejection
The Role of Corticosteroids and Cyclosporin A in Prevention of Corneal Graft Rejection // Klinička medicina, 5 (1998), 1; 37-43 (podatak o recenziji nije dostupan, članak, stručni)
CROSBI ID: 25458 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
The Role of Corticosteroids and Cyclosporin A in Prevention of Corneal Graft Rejection
Autori
Karaman, Željka ; Gabrić, Nikica ; Mravičić, Ivana ; Mitrović, Sanja ; Raštegorac, Petar
Izvornik
Klinička medicina (1330-058X) 5
(1998), 1;
37-43
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni
Ključne riječi
Corneal transplantation; Corticosteroids; Cyclosporin A
Sažetak
The most frequently mentioned postkeratoplasty complication is corneal graft rejection, caused by introduction of different tissue antigens into the organism. The cornea is considered as "immunologicaly privileged" part of the eye, because of the absence of blood and lymphatic vessels in the healthy cornea (the afferent and efferent limb for immune reaction lacks), and also because of the phenomena called ACAID (Anterior Chamber Associated Immune Deviation), which main characteristic is a cellular immunity depression. In spite of appearance of new generations of immunosuppressors, corticosteriod therapy is the most frequently used for maintenance of keratotranspalntat and prevention of rejection. Another drug which is today more frequently in use is Cyclosporin A (CsA), a potent immunosupresive agent isolated from certain fungi soil.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
