Pregled bibliografske jedinice broj: 254481
Effects of L-(2 adamantyl)-glycyl-L alanyl-D-isoglutamine hydrochloride on MCa mammary carcinoma
Effects of L-(2 adamantyl)-glycyl-L alanyl-D-isoglutamine hydrochloride on MCa mammary carcinoma // Abstracts of The 4th International Conference on Anticancer Research, Crete, Greece, 21.10.-25.10. 1992.
Kreta, Grčka, 1992. str. 1983-1984 (poster, međunarodna recenzija, sažetak, znanstveni)
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Naslov
Effects of L-(2 adamantyl)-glycyl-L alanyl-D-isoglutamine hydrochloride on MCa mammary carcinoma
Autori
Sava, Gianni ; Pacor, S. ; Cocchietto, M. ; Vranešić, Branka ; Tomašić, Jelka
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Abstracts of The 4th International Conference on Anticancer Research, Crete, Greece, 21.10.-25.10. 1992.
/ - , 1992, 1983-1984
Skup
4th International Conference on Anticancer Research
Mjesto i datum
Kreta, Grčka, 21.10.1992. - 25.10.1992
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
Adamantyltripeptide; mammary carcinoma; metastasis
Sažetak
Two new adamantyl-peptides, D-(2-adamantyl)-glycyl-L-alanyl-D-isoglutamine hydrochloride (isomer 1) and L-(2-adamantyl)-glycyl-L-alanyl-D-isoglutamine hydrochloride (isomer 2) , were tested in the model of the MCa mammary carcinoma of CBA mouse. These compounds, particularly Isomer 2, showed to be more effective in reducing lung metastasis than primary tumor growth and to be active in conditions in which a low number of metastases are formed, a condition that is seen when the tumor is implanted s.c. or when its growth is slowed down by the lower inoculum size.
Izvorni jezik
Engleski
Znanstvena područja
Kemija, Biologija, Temeljne medicinske znanosti
