Pregled bibliografske jedinice broj: 254427
Genotoxicity of dithiocarbamates and their metabolites
Genotoxicity of dithiocarbamates and their metabolites // Mutation Research Letters, 325 (1992), 65-74 (međunarodna recenzija, članak, znanstveni)
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Naslov
Genotoxicity of dithiocarbamates and their metabolites
Autori
Franekić, Jasna ; Bratulić, Nada ; Pavlica, Mirjana ; Papeš, Dražena
Izvornik
Mutation Research Letters (1383-5718) 325
(1992);
65-74
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Dithiocarbamates; Point reverse mutation; Aneuploidy; Mitotic disturbance; Polyploidy; Micronucleus
Sažetak
Dithicarbamate fungicides are widely used in agriculture for protection of vegetable crop and seeds. The mutagenicity spectra of ziram, thiram, zineb S-65 and ETU were determined by employing a battery of test systems included the bacterium Salmonella typhimurium (strain TA98, TA100, TA102, TA104, TA1535, TA1538), the yeast Saccharomyces cerevisiae (strain D61.M) and the shallot Allium ascalonicum somatic cells. Plate incorporation assay with S. typhimurium demonstrated direct mutagenicity of ziram in TA100 and thiram in TA100 and TA98 whereas zineb S-65 and ETU were ineffective. Tests for mitotic chromosome malsegregation in S. Cerevisiae D61.M gave positive results with thiram, zineb S-69 and ETU. In shallot somatic root-tip cells ziram, thiram and ETU induced different genetic damages e.g. mitotic disturbance, polyploidy and micronuclei.
Izvorni jezik
Engleski
Znanstvena područja
Biologija
POVEZANOST RADA
Ustanove:
Prirodoslovno-matematički fakultet, Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- SCI-EXP, SSCI i/ili A&HCI
