Naslov
Biological activity of tert- butyloxycarbonyl-L- tyrosyl peptidoglycan monomer (Boc Tyr PGM), a new derivative of PGM.
(Biological activity of tert-butyloxycarbonyl-L- tyrosyl peptidoglycan monomer (Boc Tyr PGM), a new derivative of PGM.)

Autori
Hršak, Ivo ; Ljevaković, Đurđica ; Tomašić, Jelka

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Program and Abstracts, International Symposium on Immunotherapy of Infections, Berlin, Germany, 04.05.- 07.05. 1993. / - , 1993, 112-112

Skup
International Symposium on Immunotherapy of Infections

Mjesto i datum
Berlin, Njemačka, 04.05.1993. - 07.05.1993

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
tert-butyloxycarbonyl-L-tyrosyl peptidoglycan monomer; biological activity; immunostimulating activity; melanoma B-16; peptidoglycan
(tert-butyloxycarbonyl-L-tyrosyl peptidoglycan monomer; biological activity; melanoma B-16; peptidoglycan)

Sažetak
Boc-Tyr-PGM is a new synthetic derivative of PGM prepared by coupling of tyrosine to the peptide portion of the molecule. Introdution of the tyrosyl moiety enabled the labeling with radioactive iodine and subsequent application of labeled compound in the radioimmunoassay of PGM. In experimental models in mice, Boc-Tyr-PGM exhibited immunostimulating and antimetastatic activities.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biologija, Temeljne medicinske znanosti

POVEZANOST RADA