Naslov
Redox kinetics of adriamycin adsorbed on the surface of graphite and mercury electrodes

Autori
Komorsky-Lovrić, Šebojka

Izvornik
Bioelectrochemistry (1567-5394) 69 (2006); 82-87

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Adriamycin; Doxorubicin; Kinetics; Redox reaction; Surface; Graphite electrode; Mercury electrode; Square-wave voltammetry

Sažetak
Kinetics of the surface redox reactions of adriamycin (doxorubicin hydrochloride) adsorbed on paraffin-impregnated graphite electrode (PIGE) and on mercury electrode is measured by square-wave voltammetry. In 0.9 mol/L KNO3 buffered to pH 4.65, the standard electrode reaction rate constants of the first quinine / hydroquinone redox couple (see Scheme 2) on PIGE and mercury are ks1= 49  12 s-1 and ks1 = 147  36 s-1, respectively. Under the same conditions, the standard rate constant of the second redox couple on the PIGE is smaller than 4 s-1 and the electron transfer coefficient of the reduction is  2 = 0.35.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

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