Pregled bibliografske jedinice broj: 252445
Electrochemical characterization of simvastatin by abrasive stripping and square-wave voltammetry
Electrochemical characterization of simvastatin by abrasive stripping and square-wave voltammetry // Journal of electroanalytical chemistry (1992), 593 (2006), 1-2; 125-130 doi:10.1016/j.jelechem.2006.03.026 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 252445 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Electrochemical characterization of simvastatin by
abrasive stripping and square-wave voltammetry
Autori
Komorsky-Lovrić, Šebojka ; Nigović, Biljana
Izvornik
Journal of electroanalytical chemistry (1992) (1572-6657) 593
(2006), 1-2;
125-130
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
simvastatin ; statins ; graphite electrode ; mercury electrode ; abrasive stripping voltammetry ; cyclic voltammetry ; square-wave voltammetry
Sažetak
The electrochemical characteristic of the lipid- lowering drug simvastatin were investigeted on graphite and mercury electrode. Solid microparticles of simvastatin were mechanically immobilized on the surface graphite electrode and immeresed into aqueous electrolyte. The microparticles were oxidized at 1.1. V in totally irreversible electrode reaction. Simvastatin dissolved in acetronitrile and admixed with 0.1 M Na2B4O7-KH2PO4 aqueous buffered solution pH 7 is strongly adsorbed of surface mercury elecreode. Adsorbed simvastatin was reduced at -1.45 V in the fast and reversible electrode reaction by a chemical reaction.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Projekti:
0098123
Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb,
Institut "Ruđer Bošković", Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
