Pregled bibliografske jedinice broj: 251265
In vitro Activity of Six Antipseudomonal Agents against 84 Pseudomonas aeruginosa Strains Isolated from Dogs Determined by the E-Test
In vitro Activity of Six Antipseudomonal Agents against 84 Pseudomonas aeruginosa Strains Isolated from Dogs Determined by the E-Test // Cesar 2006. Book of Abstracts / Dwornicek i sur. (ur.).
Bratislava: Dwornicek i sur., 2006. str. O14-014 (predavanje, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 251265 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
In vitro Activity of Six Antipseudomonal Agents against 84 Pseudomonas aeruginosa Strains Isolated from Dogs Determined by the E-Test
Autori
Šeol, Branka ; Naglić, Tomo ; Bedeković, Maja
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Cesar 2006. Book of Abstracts
/ Dwornicek i sur. - Bratislava : Dwornicek i sur., 2006, O14-014
Skup
CESAR 2006. Central European Symposium on Antimicrobial Resistance
Mjesto i datum
Vysoké Tatry, Slovačka, 18.06.2006. - 21.06.2006
Vrsta sudjelovanja
Predavanje
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
antipseudomonal agents; Pseudomonas aeruginosa; dogs; E-test
Sažetak
Ciprofloxacin, enrofloxacin, gentamicin, cefipime ceftazidime and ticarcillin-clavulanic acid were tested by the E-test against 84 Pseudomonas aeruginosa strains. Ceftazidim was the most active agent with 100% of isolates having a MIC ≤ 8 mg/L (range 0.38 – 6). Ciprofloxacin and ticarcillin-clavulanic had similar activity 76% and 73% were inhibited by a MIC ≤ 1 mg/L (range 0.064 -1) and a MIC ≤ 64 mg/L (range 4 -64) respectively. Cefipime inhibited 50% of tested strains with a MIC ≤ 8 mg/L of (range 0.75 – 8). Gentamicin was the least active with 42% of P. aeruginosa isolates having a MIC ≤ 4 (range 0.125 – 16). Interpretative criteria for enrofloxacin are provide by the CLSI veterinary guidelines (M31-A2, 2002) and refer to the specific animal being treated. The CLSI guidelines state that for canine and feline Gram negative enteritic bacilli and other susceptible microorganisms, the breakpoints are S≤ 0.5, F= 1-2 and R ≥ 4, where F indicates the availability of FDA-approved labeling and those microorganisms should be considered susceptible if dosing modifications found in the package insert are applied. According to CLSI none of 84 tested strains were susceptible to enrofloxacin, 57% (48 strains) were resistant with a MIC range 3 – 32 mg/L and 43% (36 strains) having a MIC range 0.75 – 3mg/L, were ranged as category F.
Izvorni jezik
Engleski
Znanstvena područja
Veterinarska medicina
