Naslov
Residual and recurrent lesions after conization for cervical intraepthelial neoplasia grade 3

Autori
Milojkovic, Miodrag

Izvornik
International journal of Gynecology and Obstetrics (0020-7292) 76 (2002); 49-53

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, ostalo

Ključne riječi
Cervical intraepithelial neoplasia grade 3; Conization; Residual and recurrent lesion.

Sažetak
Objective. To evaluate the importance of regular and long-term follow-up of patients who had conization for cervical intraepithelial neoplasia grade 3(CIN3) ; to assess the risk of residual/recurrent lesions of the cervix uteri. Methods. Retrospective analysis of 934 patients with CIN 3 who underwent conization over the period 1 January 1985 – 31 December 1997. An analysis of 38 (4, 1%) patients who had involved resection margins and 896 (95.9%) patients who had free resection margins. Results. Twenty-three out of 934 (2, 5%) patients had another operation (reconization in 17 and hysterectomy in 6) whereas one patient had biopsy. Residual or recurrent lesion after conization was found in 23 patients out of 934 (2, 5%). Three patients had invasive cervical cancer (0.3%), 19 had CIN 3 (2.0%) and CIN 1 one patient (0.1%). One of the 24 patients (4.2%) was diagnosed with no lesion after repeated operation. Eleven patients out of 38 (28, 9%) with involved resection margins during the first conization had residual/recurrent disease, compared with eight out of 896 patients (0.9%) who had free resection margins. Conclusion. Another operation is recommended only in cases when, on the basis of cytological, colposcopical and histological findings, the gynecologist suspect the residual/recurrent lesions.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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