Pregled bibliografske jedinice broj: 248404
Synthesis of 1, 8-Dioxa-dibenzo[e, h]azulenes
Synthesis of 1, 8-Dioxa-dibenzo[e, h]azulenes // Journal of Heterocyclic Chemistry, 43 (2006), 749-754 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 248404 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Synthesis of 1, 8-Dioxa-dibenzo[e, h]azulenes
Autori
Pešić, Dijana ; Ozimec Landek, Ivana ; Merćep, Mladen ; Mesić, Milan
Izvornik
Journal of Heterocyclic Chemistry (0022-152X) 43
(2006);
749-754
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
anti-inflammatory; antipsychotic; cardiovascular; drugs; dibenzo[e; h]azulenes
Sažetak
A novel synthetic route to 2-methyl-1, 8-dioxa-dibenzo[e, h]azulenes via cyclisation of the corresponding 1, 4-dicarbonyl compound is described. 1, 4-Dicarbonyl compounds were synthesized by the alkylation reaction of the 11H-dibenzo[b, f]oxepine-10-one while analogous alkylation of 11H-dibenzo[b, f]thiepine-10-one resulted in formation of O-alkylated products. Selective oxidation of 2-methyl group afforded 1, 8-dioxa-dibenzo[e, h]azulenes with formyl and hydroxymethyl functionality at C(2) position.
Izvorni jezik
Engleski
Znanstvena područja
Kemija, Biologija, Temeljne medicinske znanosti
POVEZANOST RADA
Ustanove:
Pliva-Istraživački institut
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
