Pregled bibliografske jedinice broj: 248106
Excitotoxic hippocampal neuron loss following sustained electrical stimulation of the perforant pathway in the mouse
Excitotoxic hippocampal neuron loss following sustained electrical stimulation of the perforant pathway in the mouse // Brain Research, 1085 (2006), 1; 195-198 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 248106 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Excitotoxic hippocampal neuron loss following sustained electrical stimulation of the perforant pathway in the mouse
Autori
Kienzler, Friederike ; Jedlicka, Peter ; Vukšić, Mario ; Deller, Thomas ; Schwarzacher, Stephan W.
Izvornik
Brain Research (0006-8993) 1085
(2006), 1;
195-198
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Epilepsy; Seizure; Epileptic brain damage; Dentate gyrus; Hilus
Sažetak
Prolonged electrical stimulation of the perforant pathway in the rat evokes epileptiform discharges in dentate granule cells and irreversibly damages hilar neurons. In this in vivo study, we demonstrate that similar perforant path stimulation in C57Bl/6 mice causes the same pattern of hippocampal neuron loss. Therefore, this mouse model of seizure-induced hippocampal injury can be used for a wide variety of studies in genetically altered conditions not available in rats.
Izvorni jezik
Engleski
POVEZANOST RADA
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
Uključenost u ostale bibliografske baze podataka::
- Chemical Abstracts
- Chemical Abstracts
- PsycINFO Psychological Abstracts
