Naslov
Epilepsy and pregnancy

Autori
Šepić-Grahovac, Dubravka ; Sepčić, Juraj ; Petrović, Oleg ; Pavešić, Danilo

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Epilepsia, Vol 38, suppl. 3, Abstracts / - Dublin : Lippincott-Raven publ., 1997

Skup
22nd International Epilepsy Congress

Mjesto i datum
Dublin, Irska, 29.06.1997. - 04.07.1997

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Epilepsy; pregnancy

Sažetak
Pregnancy usually poses no problem to the vast majority of women with epilepsy. Antiepileptic drugs (AEDs) carry a small (7-10%) but significant risk of producing fetal abnormalities. We analysed 59 pregnant women with epilepsy, aged from 19-47. Forty-three (72, 8%) were affected till the age of 23. 50.9% were taking antiepileptic drugs during pregnancy ; 83.3% as monotherapy and 16.7% as polytherapy. The most common drug was valproate (40%), carbamazepine and Phenobarbital (36.7% both) and the rarest was phenytoin (6.7%). Miscarriages before the delivery were present in 14 (23.7%) patients. Fifty-two (88.1%) patients had natural deliveries and seven had Caesarean section. Fifty-nine epileptic pregnant women gave birth to 59 children. Four children had bilateral equinovarus ; one child had haemangioma on the right shoulder ; one had umbilical hernia and one had the stagnation of intrauterus growth. Our study confirms neither damages nor malformations of the fetus, influenced by antiepileptics (AEDs) treatment.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita, Farmacija

POVEZANOST RADA