Naslov
Corticodentatonigral degeneration and amyotrophy with dystrophic achromasic neurons

Autori
Monaco, Salvatore ; Sepčić, Juraj ; Cavallaro, Tiziana ; Ferrari, Silvio ; Rizzuto, Nicolo

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts of 23rd Annual Meeting of the Italian Neuropathological Association. The Italian Journal of Neurological Sciences 1987 ; 8 / Bugiani, Orso - Padova : Associazione Italiana di neuropatologia, 1987, 193-194

Skup
23rd Annual Meeting of the Italian Neuropathological Association.

Mjesto i datum
Padova, Italija, 04.06.1987. - 06.06.1987

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Corticodentatonigral degeneration; amyotrophy; achromasia; neuron
(corticodentatonigral degeneration; amyotrophy; achromasia; neuron)

Sažetak
We report on a demented patient with extrapyramidal, cerebellar and lower motor neuron involvement. He was 52 at onset of the disease and died two years later. The presenting neurological pattern was: dysphasia, agnosia and slowness of thought and movement. A year later diffuse fasciculations and marked muscular atrophy were observed in all extremities and tongue together with dysarthria, hypodiadochokinesia, Parkinson-like features and paresis of all extremities. CT scan of the brain revealed central and cortical atrophic changes with marked enlargement of the frontal and Sylvian fissures bilaterally. Gross examination revealed atrophic changes in the left parietal and upper temporal cortex ; microscopical examination showed degeneration with achromasic neurons and chromatolytic-type changes in the affected cortical regions, pigmented and motor nuclei of the brainstem, dentate nucleus and spinal cord motor neurons.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA