Naslov
Reproductive disturbance caused by an s-triazine herbicide in pigs

Autori
Gojmerac, Tihomira ; Uremović, Marija ; Uremović, Zvonimir ; Žurić, Marijan ; Ćurić, Stipica ; Bilandžić, Nina

Izvornik
Acta veterinaria Hungarica (0236-6290) 47 (1999), 1; 129-135

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
s-triazine herbicide; atrazine; reproduction gilts; oestrus estradiol-17*

Sažetak
The aim of the study was to assess the effect of subacute treatment with a low dose of atrazine (1, 3, 5- triazine- 2, 4- diamine, 6- chloro-N-ethyl-N'- (1-methylethyl), an s-triazine herbicide, on endocrine estrus regulation in gilts. A group of 9 gilts (F 1 generation of Swedish Landrace x Large Yorkshire) were daily administered 1 mg atrazine/kg body mass mixed to the feed for 19 days before the onset of the expected estrus. Blood samples were obtained by cranial vena cava puncture three times daily at 3-h intervals on five post- treatment days, i.e. before and during estrus. Serum concentration of estradiol-17* (E2) was determined by the fluoroimmunochemical method. On day -2 before the onset of the expected estrus, a significantly lower (P<0.001) E2 concentration was measured in the serum of treated gilts ( 31.25 * 1.95 and 39.32 * 1.38 pg/mL) compared to control pigs ( 51.43 * 1.29 and 68.59 * 2.99 pg/mL). In contrast, the measured concentration of E2 in the serum of treated animals was significantly higher (P<0.001) on the day of the expected onset of estrus and on the two consecutive days (35.43 * 1.85, 53.92 * 1.98 and 60.32 * 2.35 pg/mL) compared to control animals (13.52 *1.79, 21.53 * 1.35 and 20.05 * 1.46 pg/mL). Disturbance of the serum E2 concentration in the treated gilts resulted in failure of the expected estrus, as also indicated by the state of diestrus, demonstrated by histopathologic examination of the uterus.

Izvorni jezik
Engleski

Znanstvena područja
Šumarstvo

POVEZANOST RADA