Pregled bibliografske jedinice broj: 236161
Oxidative burst of neutrophils against melanoma B16-F10
Oxidative burst of neutrophils against melanoma B16-F10 // Cancer Letters, 246 (2007), 1-2; 100-108 doi:10.1016/j.canlet.2006.02.002 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 236161 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Oxidative burst of neutrophils against melanoma B16-F10
Autori
Živković, Morana ; Poljak-Blaži, Marija ; Žarković, Kamelija ; Mihaljević, Danijela ; Schaur, Rudolf Joerg ; Žarković, Neven
Izvornik
Cancer Letters (0304-3835) 246
(2007), 1-2;
100-108
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
oxidative burst; neutrophils; polymorphonuclear leukocytes; anti-cancer effects; melanoma B16-F10; Sephadex
Sažetak
Intensive oxidative burst was determined by chemiluminescence of peripheral blood neutrophils of mice that were intramuscularly injected with melanoma B16-F10 and/or subcutaneously with Sephadex G-200. The neutrophils from papula developed at the site of Sephadex injection were cytotoxic for the B16-F10 cells in vitro. However, survival of Sephadex injected tumour bearing mice was lower than of control animals bearing B16-F10, while their tumours grew faster and were less necrotic. Thus, it is likely that injection of Sephadex distracted the neutrophils from the tumour allowing faster progression of the tumour, indicating that neutrophils may have an important role in the host defence against malignant cells in the early stage of tumour development.
Izvorni jezik
Engleski
Znanstvena područja
Biologija, Temeljne medicinske znanosti
POVEZANOST RADA
Projekti:
098-0982464-2519 - Lipidi, slobodni radikali i njihovi glasnici u integrativnoj onkologiji (Žarković, Neven, MZOS ) ( CroRIS)
108-0000000-0028 - Oksidacijski stres i tumori središnjeg živčanog sustava (Žarković, Kamelija, MZOS ) ( CroRIS)
198-0000000-3104 - Uloga neutrofila i oksidacijskog stresa u operacijama kolorektalnog karcinoma (Stipančić, Igor, MZOS ) ( CroRIS)
Ustanove:
Institut "Ruđer Bošković", Zagreb,
Medicinski fakultet, Zagreb,
Klinički bolnički centar Zagreb
Profili:
Marija Poljak-Blaži
(autor)
Kamelija Žarković
(autor)
Neven Žarković
(autor)
Danijela Kolenc
(autor)
Morana Jaganjac
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE