Pregled bibliografske jedinice broj: 23535
Prediction of Bendability and Curvature in Genomic DNA
Prediction of Bendability and Curvature in Genomic DNA // Periodicum biologorum, 100 (1998), 2; 127-139 (podatak o recenziji nije dostupan, znanstveni)
CROSBI ID: 23535 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Prediction of Bendability and Curvature in Genomic DNA
Autori
Gabrielian, A. ; Vlahoviček, K. ; Munteanu, M.G. ; Gromiha, M.M. ; Brukner, I. ; Sanchez, R. ; Pongor, S.
Izvornik
Periodicum biologorum (0031-5362) 100
(1998), 2;
127-139
Ključne riječi
DNA bending; DNA models; DNA curvature; Internet server
Sažetak
The dynamic ability of DNA molecule to bend is thought to be a crucial factor in processes such as gene regulation, packaging and DNA replication. DNA bendability and curvature propensity of shorter DNA segments can be estimated based on parameters derived from deoxy-ribonuclease I cleavage experiments using a sequence-dependent anisotropic bendability (SDAB) model of DNA. This is a simplified elastic rod model in which sequence-dependence, the anisotropy, and the helical symmetry of bending rigidity are explicitly considered. Here we outline the development of this model and present a set of tools for as well as preliminary results on predictive analysis of genomic DNA.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Projekti:
119407
Ustanove:
Prirodoslovno-matematički fakultet, Zagreb
Profili:
Mirko Brukner
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus