Pregled bibliografske jedinice broj: 234300
Trefoil factor family 2 deficiency and immune response
Trefoil factor family 2 deficiency and immune response // Cellular and molecular life sciences, 62 (2005), 24; 2947-2955 doi:10.1007/s00018-005-5483-7 (međunarodna recenzija, pregledni rad, znanstveni)
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Naslov
Trefoil factor family 2 deficiency and immune response
(Trefoil factor family 2 defi ciency and immune response)
Autori
Baus-Lončar, Mirela ; Kayademir, Tuncay ; Takaishi, S. ; Wang, Timothy
Izvornik
Cellular and molecular life sciences (1420-682X) 62
(2005), 24;
2947-2955
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni
Ključne riječi
TFF2 ; gastrointestinal defense ; TFF2 deficiency ; gene expression ; immune response
Sažetak
The protective effect of Trefoil Factor Family (TFF) proteins in the gastrointestinal tract by promoting the healing of injured mucosa is well known. An increasing body of evidence connects TFFs, especially, TFF2 and TFF3, with a possible role in immune regulation. TFF2 is able to inhibit lipopolysaccharide-induced nitric oxide production in monocytes and can potently limit leukocyte recruitment at the site of injury. An analysis of gene expression in gastrointestinal tissue of TFF2-deficient mice reveals some new aspects of TFF2’ s role in the immune response.
Izvorni jezik
Engleski
Znanstvena područja
Biologija, Temeljne medicinske znanosti
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
