Naslov
HLA antigens of multiple sclerosis patients in Istria, western Croatia

Autori
Strenja-Linić, Ines ; Sepčić, Juraj ; Vujaklija-Stipanović, Ksenija ; Crnić-Martinović, Marija ; Rudež, Josip ; Antonelli, Licia ; Materljan, Eris ; Stojanović, Dražen

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstaracts of the 15th Congress of the European Commitee for Treatment and Research in Multiple Sclerosis, ECTRIMS 1999 ; u: Multiple Sclerosis. Supplement (ISSN 1361-2433) 5 (1999) (S1) / - Basel, 1999, S32-S32

Skup
15th Congress of the European Commitee for Treatment and Research in Multiple Sclerosis : ECTRIMS 1999 (15 ; 1999)

Mjesto i datum
Basel, Švicarska, 18.09.1999. - 21.09.1999

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
antigenes; HLA; multiple sclerosis

Sažetak
This study analysis HLA antigenes in native population of MS patients in Istria, western Croatia, area of a high risk for MS (prevalence about 45/100000 hab.). The patients were selected by Poser's diagnostic criteria for MS. The control group consisted of unrelated natives of Istria, chosen at random who were not hosts of hereditary diseases. The distribution of HLA antigens was tested with relative risk (RR test), etiologic (EF) and preventive (PF) factors. MS patients in Istria show an increased RR for antigens DR2 (RR 4.012), B18 (RR 2.111), A2 (RR 1.918) and A1 (RR 1.745). The highest value of EF was found for the antigens DR3 (EF 0.027) and the highest value of PF was found for the antigens B14 (PF 0.163). The research confirms the association of the antigen DR2 with MS patients on the Mediterranien coast.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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