Naslov
Inhlation anaesthetics- new method of sedation in ICU

Autori
Brozović, Gordana ; Kvolik, Slavica ; Lučić, Ivo

Izvornik
Neurologia Croatica (0353-8842) 53 (2004), Supl. 2; 113-118.

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, stručni

Ključne riječi
Inhalation anaesthetics; Isoflurane; Sevoflurane; Anaesthetic techniques; Sedation

Sažetak
Inhalation is a dependable route of drug administration and elimination. Drugs administered via this route generally have a rapid onset of action and the recovery period is short. The desired level of sedation can be titrated rapidly, ranging from a light level to that approaching a general anaesthetic. Inhalation anaesthetic isoflurane and sevoflurane may be advantageous when used for sedation of patients in the ICU. Inhalation anaesthetics can also precondition the myocardium against functional depression and infarction following ischaemia-reperfusion. These may protect the liver from early ischemia-reperfusion injury by acting during the reperfusion phase after ischaemia or transplantation, too. It is now possible to deliver accurate concentrations of inhalation anaesthetic agents by ventilators with suitable ventilatory functions for use in the ICU. The most important part of system is disposable recirculating anaesthesia delivery system containing activated carbon fibres that enables the use of anaesthetic gases for sedation in the ICU. Anaesthetics can be delivered by syringe attached to perfusion pump. Active carbon absorbs inhaled anaesthetics used in this system during the expiratory phase ad releases those in the inspiration. Thus, the most (90%) of gas during inspiration comes from active carbon and minor portion of anaesthetic comes from syringe pump. A gas monitor immediately indicates gas concentrations. Adjustments of concentrations can be achieved rapidly. Adequate humidification is provided without circuit condensation. The system is appropriate for use in mechanically ventilated adult patients only, not for spontaneously breathing patients and for children. It is not appropriate for use with other inhaled anaesthetics and nitrous oxide.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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